The ISB is a laboratory building used by various scientists and researchers. The floors are steel and concrete composite framing, the roof is heavy steel, the entry canopies are glue-laminated timer, and the foundation is 12-inch thick conventional cast-in-place concrete on spread/strip footings. Allowable soil bearing pressure is 8,000 psf. About 100 tons of mechanical equipment is housed in the mechanical penthouse which is efficiently located under the tallest portion of the roof. Two heavy steel trusses support the roof and four levels of concrete floors over the extra-large lecture room on the first floor. Seismic and wind forces are resisted with steel seismic towers anchored to the foundation with 2 ½-inch diameter steel rods.